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When a measurable value like the oxygen isotope ratio is determined by many discrete and different influences, it can only be used as a proxy for one of them, if and when all others are either held constant or reliably corrected for. At the height of the Ice Age with its huge amount of water trapped in glaciers the composition of the ultimate source, sea water, was noticeably different. That’s what marine isotope stages are based on. The airflow patterns too were dissimilar from today’s. None of that is considered or corrected for in Pederzani et al. That said these corrections should only make their reported result stronger.
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